structural-biology meet

Scientists have measured for the first time at the nanometer scale the characteristic patterns of folds responsible for proteins to know their three-dimensional shape in water with the help of the method developed earlier. With the help of this technique, scientists will be able to gain insights about the behavior of biomolecules in watery environments. These insights will result into increase in understanding the major diseases including Alzheimer's , that are related to "mistakes" in protein folding. We would not be able survive life if proteins didn't fold into precise patterns resulting into helices, sheets and other shapes that give proteins their three-dimensional structure. The precise shapes of p  Scientists have measured for the first time at the nanometer scale the characteristic patterns of folds responsible for  proteins  to know their  three-dimensional shape  in water with the help of the method developed earlier. With the help of this techniqu

To prevent the effects of  alpha-synuclein  in the brain, a tiny particle of cerium oxide is used which is compound with antioxidant properties a representing a new therapeutic treatment for the  Parkinson’s disease.  Several factors are there that contributes to Parkinson’s disease progression, including the accumulation of alpha-synuclein proteins inside nerve cells and the formation of toxic protein aggregates called  Lewy bodies.  Efforts have been made by the researchers to develop pharmacological  approaches  capable of fighting Parkinson’s disease, but no effective solution has been found. Most pharmacological compounds are non- specific, resulting in severe side effects. Most of the available compounds are unable to cross the blood-brain barrier which is a semipermeable membrane protecting the brain and are not able to reach the nerve cells affected by Parkinson’s. The  utilization of nanoparticles loaded with an active agent  has shown some promise in overcoming the

  Carbohydrate , Carbohydrate, Carbohydrate. The ‘other’ c-word that truly divides rooms. Should we eat them? Are they terrible for our health? Are brown ones better than white ones? Why are they so demonized? Carbohydrates are an integral part of any diet, but the amount that works within someone’s diet is a grey area—meaning what works for one person may not work for another. If we are used to feeling a bit on the side of life after consuming carbohydrate, it should be known that carbohydrate intolerance is totally a thing and should be taken into consideration when assessing which type of diet is best for us. What is carbohydrate intolerance? Carbohydrate intolerance is the failure to digest one or many carbohydrates due to a lack of one or more gastrointestinal enzymes. The symptoms may include diarrhea, bloating, nausea and flatulence, an official diagnosis can be made by a hydrogen or methane breath test.                                          How do we t